Oxycodone is a strong painkiller used for moderate to severe pain. It works by blocking pain signals in your body. Oxycodone activates opioid receptors in the nervous system, and it’s prescribed when other pain meds don’t work well or aren’t tolerated.
Oxycodone comes in different forms like slow-release tablets, regular tablets, capsules, oral liquids, and fast-acting injections. The fast-acting types are for when you need quick relief from short-term pain, while the extended-release tablets are for treating serious and long-lasting pain. Just remember, the extended-release products shouldn’t be used for immediate pain relief.
You can take oxycodone by itself for pain relief (Oxycontin, Roxicodone), or you can get it mixed with acetaminophen (Percocet).
Oxycodone side effects
Common oxycodone side effects
Common oxycodone side effects are:
- headache,
- constipation,
- feeling sick (nausea),
- feeling sleepy (drowsiness),
- dizziness,
- tiredness,
- stomach pain,
- vomiting,
- itching, red eyes, or flushing.
Serious oxycodone side effects
If you notice hives, difficulty breathing, or swelling of your face, lips, tongue, or throat after taking oxycodone, seek emergency medical help right away.
If you’re taking this medicine or any other opioid, it could slow or even stop your breathing, which could be really dangerous. If someone notices you’re breathing slowly, have long pauses, blue lips, or are hard to wake up, they should give you naloxone and get emergency help right away.
Call your doctor at once if you have:
- noisy breathing, sighing, shallow breathing, breathing that stops during sleep;
- a slow heart rate or weak pulse;
- cold, clammy skin;
- a light-headed feeling, like you might pass out;
- confusion, unusual thoughts or behavior;
- seizure (convulsions);
- low cortisol levels – nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness; or
- high levels of serotonin in the body – agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea.
Older adults, as well as those who are frail or have conditions like wasting syndrome or chronic breathing disorders, are more likely to experience serious breathing problems.
Using opioid medication for a long time, like this one, might affect the ability to have children in men or women. It’s not known if these effects on fertility are permanent.
Before taking this medicine
You should not use oxycodone if you are allergic to it or if you have:
- severe asthma or breathing problems; or
- a blockage in your stomach or intestines.
If you’re already taking a similar opioid medicine and have built up a tolerance to it, don’t take this medicine. Also, if you’ve used a MAO inhibitor like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine in the past 14 days, or have had a methylene blue injection, avoid using this medicine.